Lower rate limit in cardiac resynchronization therapy defibrillators

Abstract Background There is few data about programmed lower rate limit (LRL) in real world heart failure (HF) patients with cardiac resynchronization therapy–defibrillators (CRT-Ds) and its influence clinical outcomes. Heart score (HRS) the percentage of all atrial-paced sensed events single tallest 10 beats/min device histogram bin may indicate impaired variability. Purpose We hypothesized that higher LRL programming associated worse outcomes as arrhythmic HF decompensations chronic CRT-Ds. Methods was evaluated HRS calculated from remote monitoring 126 CRT-D. Primary outcome defined hospitalizations related admissions to emergency department secondary number therapies, sustained ventricular tachycardia (VT) fibrillation (VF). Results Mean age 69,03±10,39 years, 81 (64,3%) were males mean follow-up 53,72±46,13 months. left ejection fraction 30,31±8,33% 29 (23,0%) NYHA III–IV. aetiology idiopathic 39 (43,3%), ischemic 32 (25,4%) alcoholic cardiomyopathy 8 (6,3%). Thirty-seven (29,4%) had atrial 33 (26,2%) coronary disease. ranged 40 80 bpm 52,64±9,64 49,60±23,17%. Programmed women (p=0,014), (AF) (p=0,012) disease (p=0,015). Higher correlated (ED) (r=0,541, p=0,001), VT or VF episodes (r=0,337, p=0,005) CRT-D therapies (r=0,342, p=0,004) (r=0,547, p<0,05). Conclusion HRS, hospitalization admission department, a population. More studies are required but be preferred patients. Funding Acknowledgement Type funding sources: None.